Kybella ATX-101 is the first and only FDA-approved drug also known as a “double-chin” that addresses submental fullness. Kybella is used without surgery to contour the jawline and permanently remove fat under the chin. Kybella contains a natural ingredient called deoxycholic acid, something that is already created by your body. This ingredient kills fat cells permanently. Afterwards, fat can no longer be retained or accumulated by certain cells. Liposuction or surgery have been the only choices for removing liposuction for years.